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Symbol
Name
ID
Stx11
syntaxin 11
MGI:1921982
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations
Human Phenotypes
Anemia
Neutropenia
Hemophagocytosis
Hypofibrinogenemia
Thrombocytopenia
Splenomegaly
Disease(s) Associated with STX11
familial hemophagocytic lymphohistiocytosis 4

Mouse Phenotypes
decreased NK cell degranulation
decreased erythrocyte cell number
decreased neutrophil cell number
thrombocytopenia
increased lymphocyte cell number
decreased leukocyte cell number
pancytopenia
abnormal neutrophil physiology
abnormal lymphocyte physiology
impaired natural killer cell mediated cytotoxicity
abnormal cytotoxic T cell physiology
decreased cytotoxic T cell cytolysis
Availability Mouse Genotype
Stx11em1(IMPC)Mbp/Stx11em1(IMPC)Mbp
Stx11tm1.2Ics/Stx11tm1.2Ics
Stx11tm1Bupa/Stx11tm1Bupa

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory